Long filopodia and tunneling nanotubes define new phenotypes of breast cancer cells in 3D cultures

Long filopodia and tunneling nanotubes define new phenotypes of breast cancer cells in 3D cultures

Most cancers cell invasion into the encircling extracellular matrix (ECM) takes place when cell-cell junctions are disrupted upon epithelial-to-mesenchymal transition (EMT). Each most cancers cell-stroma and cell-cell crosstalk are important to help the continual tumor invasion. Most cancers cells launch microvesicles and exosomes containing bioactive molecules and sign peptides, that are recruited by neighboring cells …

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